| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 9
| Issue : 2 | Page : 159-163 |
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Histomorphological analysis of nephrectomy specimens: Experience at a tertiary care institute
BM Soumya1, Rajkumari Jayshree Devi1, Sriharsha Kulkarni2, Vardendra G Kulkarni1
1 Department of Pathology, JJMMC, Davanagere, Karnataka, India
2 Department of General Medicine, SSIMS and RC, Davanagere, Karnataka, India
Correspondence Address:
Dr. Sriharsha Kulkarni
Department of General Medicine, SSIMS and RC, Davanagere, Karnataka
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/amit.amit_93_22
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Introduction: For a range of kidney abnormalities, including both neoplastic and nonneoplastic disorders, nephrectomy is a popular surgical treatment. We conducted this study to examine the range of lesions found in the nephrectomy specimens obtained and to ascertain the distribution of these lesions by age and sex. Materials and Methods: This study was conducted in the department of pathology, from 2017 to 2022. All nephrectomy specimens received during 5 years were included. Results: The spectrum of renal lesions observed in the study included both neoplastic (43.75%) and nonneoplastic (56.25%) conditions. Nineteen patients were males (59.37%) and 13 were females (40.62%) (M: F = 1.4:1). The most common entity in the nonneoplastic category was chronic pyelonephritis (n = 9, 28.12%). In our study, we documented two unusual cases of renal replacement lipomatosis (RRL), a type of pseudotumor related to nonfunctioning kidneys. Fourteen patients underwent nephrectomy for neoplastic conditions such as Wilm's tumor and renal cell carcinoma (RCC). Conclusion: Nephrectomy for the nonneoplastic condition was performed more frequently in our series. Histopathological evaluation of nonneoplastic nephrectomy specimens must be thoroughly considered, particularly in unusual circumstances such as RRL, where a preoperative erroneous initial impression of a malignant lesion such as angiomyolipoma or liposarcoma is possible.
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