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Year : 2015  |  Volume : 2  |  Issue : 2  |  Page : 130-134

Genetics in psychiatry – diagnostic support or an illness classification!

1 Instructor, Department of Psychiatry, Aga Khan University Hospital, Karachi, Pakistan
2 Resident Medical Officer, Sind Institute of Urology and Transplantation, Karachi, Pakistan

Correspondence Address:
Hena Jawaid
Instructor, Department of Psychiatry, Aga Khan University Hospital, Karachi
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Source of Support: None, Conflict of Interest: None

DOI: 10.5530/ami.2015.4.4

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Psychiatric diseases and their diagnosis are basically dependent upon phenomenology, other than a few conditions where the focus is on purely the medical condition. The changing and evolving picture of psychiatric nosology inculcates genetic findings as well. It has helped clinicians in understanding the disease pathology, its course, prognosis and the intervention options. This comprehensive, pedagogically-oriented review is aimed to include different advancements in genetic association studies along with various terms and findings in psychiatry, which have facilitated deeper understanding of illness at the molecular level. Findings on Alzheimer's disease, Autism spectrum disorder, schizophrenia and eating disorders are discussed. Existing interventions can be further modified by addition of modulators, inhibitors of A-beta aggregation, immunotherapy and inhibitors which can be generated on the basis of genetic association studies and its findings.

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