Close
  Indian J Med Microbiol
 

Figure 1: Cytotoxic effect of Tarantula cubensis venom on the human cells. (A) Morphological change of the cells. HEK293, MCF7 and HN5 cell lines showed aberrant adhesion morphology after treatment with 100 μg/ml of Theranekron® (Tn) for 24 h. (B) MTT cell proliferation results. The results of indicated significant decrease in proliferation of the cells under treatment with 20, 50, 100, 250 and 500 μg/ml of Theranekron® for 12, 24 and 24 h. (C) Percentages of dead cells. The cells were treated with the various concentrations of Theranekron® for the various periods as described above and then were stained with trypan blue dye. There was found significant increase in death rate of the cells under effect of Theranekron®. Absolut ethanol (Et) was used a negative control. P-values are not indicated on this figure.

Figure 1: Cytotoxic effect of Tarantula cubensis venom on the human cells. (A) Morphological change of the cells. HEK293, MCF7 and HN5 cell lines showed aberrant adhesion morphology after treatment with 100 μg/ml of Theranekron<sup>®</sup> (Tn) for 24 h. (B) MTT cell proliferation results. The results of indicated significant decrease in proliferation of the cells under treatment with 20, 50, 100, 250 and 500 μg/ml of Theranekron<sup>®</sup> for 12, 24 and 24 h. (C) Percentages of dead cells. The cells were treated with the various concentrations of Theranekron<sup>®</sup> for the various periods as described above and then were stained with trypan blue dye. There was found significant increase in death rate of the cells under effect of Theranekron<sup>®</sup>. Absolut ethanol (Et) was used a negative control. P-values are not indicated on this figure.